NAD (Nicotinamide adenine dinucleotide) is a coenzyme that participates in a variety of biochemical activities within cells. It comes in two forms: NAD+ (oxidized) and NADH (reduced). NAD functions as an electron transporter, transporting electrons from one reaction to the next, aiding energy transmission and metabolic activities.
NAD enzymes, also known as NAD-dependent enzymes, use NAD as a cofactor to perform catalytic actions. These enzymes are involved in vital cellular processes such as glycolysis, the citric acid cycle, and oxidative phosphorylation, all of which are important steps in energy production. NAD enzymes can transfer hydride ions (H-) and participate in redox processes by accepting or donating electrons.
NAD is also involved in cellular signaling and control. It acts as a substrate for enzymes known as sirtuins, which regulate gene expression, DNA repair, and stress response. NAD is also involved in other critical biological functions such as cell development, ageing, and immunological function.
Overall, NAD enzymes serve an important role in cellular metabolism, particularly in energy synthesis and cellular control.
Nicotinamide adenine dinucleotide (NAD) is a coenzyme that is essential for cellular metabolism, acting as an electron carrier in a variety of biochemical reactions. It participates in the transfer of electrons between enzymes, which is essential for cellular respiration and energy production. NAD is a niacin derivative, also known as vitamin B3, that is produced in the body from dietary niacin. It comes in two forms: NAD+ (oxidized) and NADH (reduced), each of which serves a different purpose in cellular metabolism. NAD+ is an electron acceptor, whereas NADH is an electron donor. NAD is involved in a variety of cellular processes, including DNA repair and gene expression regulation, in addition to its role in energy production. It is also important in maintaining healthy ageing and has been shown to decrease with age. In recent years, NAD has been the subject of extensive research, particularly in the areas of anti-aging and longevity. It has been researched for its potential as a therapeutic target for age-related diseases like Alzheimer’s and Parkinson’s, as well as its ability to improve overall health span.